Tumor-infiltrating lymphocyte immunotherapy comes of age: a journey of development in the Surgery Branch, NCI

The early development of tumor-infiltrating lymphocytes into an effective clinical strategy was fundamentally the work of hundreds of scientists and clinicians within the Surgery Branch of the National Cancer Institute under the leadership of Steven Rosenberg. That journey brought new insights into the tumor-immune cell interface and ultimately helped create a new first-in-class therapeutic for patients with metastatic cancer.

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Publication Details

Journal
Journal for ImmunoTherapy of Cancer
Published
2025-04-01
DOI
https://doi.org/10.1136/jitc-2025-011734
Citations
4
Primary Topic
CAR-T cell therapy research
Type
article
Field-Weighted Citation Impact
4.18
Controls
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article

Tumor-infiltrating lymphocyte immunotherapy comes of age: a journey of development in the Surgery Branch, NCI

Steven A. Rosenberg, Stephanie L. Goff
4 citations
Journal for ImmunoTherapy of Cancer
CAR-T cell therapy research
4.18
article

Tumor-infiltrating lymphocyte immunotherapy comes of age: a journey of development in the Surgery Branch, NCI

Steven A. Rosenberg, Stephanie L. Goff
article en
4 citations

Abstract

The early development of tumor-infiltrating lymphocytes into an effective clinical strategy was fundamentally the work of hundreds of scientists and clinicians within the Surgery Branch of the National Cancer Institute under the leadership of Steven Rosenberg. That journey brought new insights into the tumor-immune cell interface and ultimately helped create a new first-in-class therapeutic for patients with metastatic cancer.

Journal for ImmunoTherapy of CancerVol. 13(4)
National Cancer Institute (US)
Good health and well-being
Openalex Percentile: Top 6%
CAR-T cell therapy research
4.18
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