Pregnancy-associated hemolytic uremic syndrome

Atypical hemolytic uremic syndrome (aHUS) is associated with pregnancy or childbirth in 12–31 % of cases and can determine the prognosis of both mother and child. In recent years, more and more attention in obstetric practice has been paid to thrombotic microangiopathy (TMA) as one of the most severe pregnancy complications. Despite the fact that TMA rarely develops during pregnancy (obstetric TMA accounts for 8–18 % in the structure of all TMA forms), the high risk of developing preeclampsia, maternal and perinatal mortality, and unfavorable renal prognosis associated with this pathology determine the relevance of studying this problem.

Authors

Publication Details

Journal
Spravočnik vrača obŝej praktiki (Journal of Family Medicine)
Published
2025-03-25
DOI
https://doi.org/10.33920/med-10-2503-05
Primary Topic
Complement system in diseases
Type
article
Field-Weighted Citation Impact
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article

Pregnancy-associated hemolytic uremic syndrome

Vladimir Anatolievich Klimov
Spravočnik vrača obŝej praktiki (Journal of Family Medicine)
Complement system in diseases
article

Pregnancy-associated hemolytic uremic syndrome

Vladimir Anatolievich Klimov
article en

Abstract

Atypical hemolytic uremic syndrome (aHUS) is associated with pregnancy or childbirth in 12–31 % of cases and can determine the prognosis of both mother and child. In recent years, more and more attention in obstetric practice has been paid to thrombotic microangiopathy (TMA) as one of the most severe pregnancy complications. Despite the fact that TMA rarely develops during pregnancy (obstetric TMA accounts for 8–18 % in the structure of all TMA forms), the high risk of developing preeclampsia, maternal and perinatal mortality, and unfavorable renal prognosis associated with this pathology determine the relevance of studying this problem.

Spravočnik vrača obŝej praktiki (Journal of Family Medicine)(3)
Openalex Percentile: Top 92%
Complement system in diseases
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