Blood and urine early treatment response biomarkers in HIV-associated disseminated tuberculosis
<i>M. tuberculosis</i> DNA was detectable in urine and blood in decreasing quantity up to 14 days of standard treatment in patients with HIV-associated TB. Urine Alere LAM showed an increasing grade intensity during this period. Further research in larger groups and extended periods are needed to assess relation to clinical outcomes.
Authors
- Graeme Meintjes (ORCID: https://orcid.org/0000-0003-1196-4414)
- Robert John Wilkinson (ORCID: https://orcid.org/0000-0002-2753-1800)
- Bianca Sossen (ORCID: https://orcid.org/0000-0002-6028-3351)
- David Barr (ORCID: https://orcid.org/0000-0002-2922-9381)
- Linda Boloko (ORCID: https://orcid.org/0000-0002-2418-0048)
- Chad M. Centner (ORCID: https://orcid.org/0000-0001-7289-534X)
- Abulele Bekiswa (ORCID: https://orcid.org/0000-0002-9900-7418)
- Phiona E Namale (ORCID: https://orcid.org/0000-0003-4024-0626)
- Charlotte Schutz (ORCID: https://orcid.org/0000-0001-8329-6158)
- Marcia Vermeulen (ORCID: https://orcid.org/0009-0003-1061-150X)
Institutions
- National Health Laboratory Service (ZA)
- University of Cape Town (ZA)
- Queen Mary University of London (GB)
- The Francis Crick Institute (GB)
- Wellcome Centre for Infectious Diseases Research in Africa (ZA)
- Queen Elizabeth University Hospital (GB)
- Imperial College London (GB)
Publication Details
- Journal
- Southern African Journal of HIV Medicine
- Published
- 2025-04-09
- DOI
- https://doi.org/10.4102/sajhivmed.v26i1.1664
- Citations
- 2
- Primary Topic
- Tuberculosis Research and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 2.79