Elucidating the Role of Trem2 in Lipid Metabolism and Neuroinflammation
This study identifies Trem2 as a pivotal regulator of astrocytic lipid metabolism and neuroinflammation in AD, providing potential molecular targets for early intervention and therapeutic strategies aimed at mitigating AD progression.
Authors
- Wei Qi
- Xiaoping Lv (ORCID: https://orcid.org/0000-0002-5296-2418)
- Chaonan Liu (ORCID: https://orcid.org/0000-0003-4913-0431)
- Chenhui Zhao
- Xueli Gao (ORCID: https://orcid.org/0000-0001-8867-3311)
- Zheng Shi-min
Institutions
- Northeast Agricultural University (CN)
- Education Department of Heilongjiang Province (CN)
Publication Details
- Journal
- CNS Neuroscience & Therapeutics
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1111/cns.70338
- Citations
- 6
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 5.05
Funders
- National Natural Science Foundation of China