Anti-Candidal Efficacy of Alternative Natural Formulations as a Denture Cleansing Agent – Is Ayurveda the Answer? – An In-vitro Study

The purpose of this study was to evaluate the anti-candidal effectiveness of several household products, such as ayurvedic medicines, to established denture cleaning agents. Acrylic samples were compared to denture cleaning pills and chlorhexidine after being submerged in a variety of freshly made ayurvedic formulations, vinegar, and home bleach for 20 minutes, and the total Candida counts (CFU/4 cm<sup>2</sup>) were measured. It was discovered that vinegar (87.36%) and Clinsodent tablets (94.66%) were the most effective against <i>Candida albicans</i>. The aqueous extract of triphala (34.50%) was more effective than the hydroalcoholic extract (18.86%), according to the ayurvedic product's data. Commercial denture cleaner was shown to have the strongest anti-candidal efficacy. In terms of anti-candidal potency, the inexpensive Triphala churna, which has been used in rural India, is not far behind.

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Publication Details

Journal
Journal of Pharmacy And Bioallied Sciences
Published
2025-04-09
DOI
https://doi.org/10.4103/jpbs.jpbs_123_25
Primary Topic
Oral microbiology and periodontitis research
Type
article
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article

Anti-Candidal Efficacy of Alternative Natural Formulations as a Denture Cleansing Agent – Is Ayurveda the Answer? – An In-vitro Study

Rahul Paul, Kritika Rajan, Ishan Roy Choudhury, Richa Bansal et al.
Journal of Pharmacy And Bioallied Sciences
Oral microbiology and periodontitis research
article

Anti-Candidal Efficacy of Alternative Natural Formulations as a Denture Cleansing Agent – Is Ayurveda the Answer? – An In-vitro Study

Rahul Paul, Kritika Rajan, Ishan Roy Choudhury, Richa Bansal, Mradu Gupta, Dilip Kumar Pal, Abhishek Shekhar
article en

Abstract

The purpose of this study was to evaluate the anti-candidal effectiveness of several household products, such as ayurvedic medicines, to established denture cleaning agents. Acrylic samples were compared to denture cleaning pills and chlorhexidine after being submerged in a variety of freshly made ayurvedic formulations, vinegar, and home bleach for 20 minutes, and the total Candida counts (CFU/4 cm<sup>2</sup>) were measured. It was discovered that vinegar (87.36%) and Clinsodent tablets (94.66%) were the most effective against <i>Candida albicans</i>. The aqueous extract of triphala (34.50%) was more effective than the hydroalcoholic extract (18.86%), according to the ayurvedic product's data. Commercial denture cleaner was shown to have the strongest anti-candidal efficacy. In terms of anti-candidal potency, the inexpensive Triphala churna, which has been used in rural India, is not far behind.

Journal of Pharmacy And Bioallied SciencesVol. 17(Suppl 1)
Ministry of Health (MY), University of Delhi (IN), Dr. R. Ahmed Dental College and Hospital (IN), West Bengal University of Health Sciences (IN), Government of Malaysia (MY)
Openalex Percentile: Top 92%
Oral microbiology and periodontitis research
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