Comparative Analysis of Primary Sarcopenia and End‐Stage Renal Disease–Related Muscle Wasting Using Multi‐Omics Approaches
We identified distinct multi-omic signatures in individuals with ESRD or sarcopenia, providing new insights into the mechanisms underlying ESRD-related muscle wasting, which differ from primary sarcopenia. These findings may support interventions for context-dependent muscle loss and contribute to the development of targeted treatments and preventive strategies for muscle wasting.
Authors
- Sang Hyeon Ju
- Evonne Kim (ORCID: https://orcid.org/0000-0002-6312-4014)
- Ha Thi Nga (ORCID: https://orcid.org/0000-0001-5593-6488)
- Hyon‐Seung Yi (ORCID: https://orcid.org/0000-0002-3767-1954)
- Jingwen Tian (ORCID: https://orcid.org/0000-0003-3500-4821)
- Hyun Suk Shin (ORCID: https://orcid.org/0000-0001-6018-505X)
- Seong‐Kyu Choe (ORCID: https://orcid.org/0000-0002-2102-973X)
- Daiki Setoyama (ORCID: https://orcid.org/0000-0002-4514-7546)
- Dae Eun Choi (ORCID: https://orcid.org/0000-0003-2870-3958)
- Ho Yeop Lee (ORCID: https://orcid.org/0000-0003-3812-9355)
- Obin Kwon (ORCID: https://orcid.org/0000-0002-3702-7202)
- Hyo Ju Jang (ORCID: https://orcid.org/0009-0000-1420-4491)
- Dohyun Han (ORCID: https://orcid.org/0000-0002-0841-1598)
- Thi Linh Nguyen (ORCID: https://orcid.org/0000-0002-6237-4767)
- Ji Sun Moon (ORCID: https://orcid.org/0000-0001-7644-0289)
Institutions
- Seoul National University (KR)
- Chungnam National University (KR)
- Seoul National University Hospital (KR)
- Kyushu University Hospital (JP)
- Wonkwang University (KR)
Publication Details
- Journal
- Journal of Cachexia Sarcopenia and Muscle
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1002/jcsm.13749
- Citations
- 3
- Primary Topic
- Nutrition and Health in Aging
- Type
- article
- Field-Weighted Citation Impact
- 3.49
Funders
- Korea Health Industry Development Institute
- National Research Foundation of Korea