Ultrasound neuromodulation for treatment-resistant depression: A case for deep brain stimulation

Ultrasound neuromodulation for treatment-resistant depression: A case for deep brain stimulation Tiago Costa from Delft University of Technology discusses why ultrasound neuromodulation has significant potential to transform the treatment of depression. Major Depressive Disorder (MDD), commonly referred to as depression, is a prevalent mental health condition affecting millions worldwide. Characterized by persistent sadness, loss of interest, and a range of emotional and physical symptoms, depression significantly impairs an individual’s quality of life. While various treatment options exist, including psychotherapy and medication, a substantial portion of individuals with depression do not respond adequately to these conventional approaches. This subset of patients, classified as having Treatment-Resistant Depression (TRD), presents a significant challenge in mental healthcare.