CYP genes and haplotypes in personalised medicine

CYP genes and haplotypes in personalised medicine Brian Tait, Chief Scientific Officer at Haplomic Technologies Pty Ltd, focuses here on CYP genes, haplotypes, and their applications in personalised medicine. Knowing the genetic phase is important as proteins are coded for by genes in a cis transfiguration. When a gene has two or more polymorphisms, it is not possible to assign protein sequences unless the genetic phase is established definitely by family studies. Currently, mathematical approaches (LD-linkage disequilibrium) are used to assign the probability of phase and long-range sequencing (LRS).