Exploring the Latest Research Trends on How Traditional Chinese Medicines Regulate Gut Microbiota to Affect the Initiation and Progression of Tumors under the Concept of “Preventive Treatment of Disease before Its Onset”

人体内最为庞大的微生态系统——肠道菌群，与肿瘤的发生、发展及其治疗手段之间，存在着密不可分的关联。近年来，中医药在肿瘤防治领域崭露头角，其通过调节肠道菌群发挥独特作用的现象，已然成为广泛关注的热点话题。该文系统梳理了中医通过调节肠道菌群对肿瘤产生影响的内在机制，重点探讨了中医如何干预肠道菌群、肠道菌群与肿瘤之间的复杂互动关系，并对这一领域在肿瘤治疗中的未来发展趋势进行了前瞻性分析。在“治未病”理念的引领下，深入探究肠道微生态与恶性肿瘤之间的内在联系，系统梳理并整合既有文献资料，旨在为中医肿瘤治疗领域开辟全新的视角与策略。The gut microbiota, the most extensive microecosystem in the human body, has an inseparable correlation with the occurrence, development, and treatment methods of tumors. In recent years, traditional Chinese medicine (TCM) has emerged prominently in the field of tumor prevention and treatment. The phenomenon that TCM exerts unique effects by regulating the gut microbiota has already become a hot topic of widespread concern. This article systematically combs through the internal mechanisms by which TCM affects tumors through the regulation of the gut microbiota, focuses on discussing how TCM intervenes in the gut microbiota and the complex interaction between the gut microbiota and tumors, and conducts a prospective analysis of the future development trends of this field in tumor treatment. Guided by the concept of “preventive treatment of disease”, this article deeply explores the internal relationship between gut microecology and malignant tumors, and systematically combs through and integrates existing literature and data, aiming to open up new perspectives and strategies for the field of TCM tumor treatment.