Research Progress of Ventilatory Ratio in Acute Respiratory Distress Syndrome

死腔通气增大反映了急性呼吸窘迫综合征(ARDS)患者主要病理生理特征，与患者死亡率密切相关。床边测量死腔的难度性促使学者们提出了一些其他评估通气效率的指标，如通气比(VR)。越来越多的研究证明VR是一个简单且稳健的床边评估指标，可应用于ARDS患者预后预测，也可能有助于其亚表型确定和呼吸管理，进而优化个体化机械通气管理与临床治疗。Enlarged dead space reflects the main pathophysiological characteristics of patients with acute respiratory distress syndrome (ARDS) and is closely related to the patient’s mortality rate. The difficulty of measuring dead space at the bedside prompted scholars to propose some other indicators to evaluate ventilation efficiency, such as ventilatory ratio (VR). More and more studies have proved that VR is a simple and robust bedside assessment indicator that can be applied to prognostic prediction of ARDS patients, and may also contribute to its subphenotype determination and respiratory management, thereby optimizing individualized mechanical ventilation management and clinical treat.