Application Mechanism and Exploration of <i>Lithospermum </i><i>erythrorhizon</i> Siebold & Zucc. in the Treatment of Perianal Eczema

肛周湿疹是慢性过敏性、非传染性疾病，是常见的肛门周围皮肤疾病，具有病程长，易复发等特点。紫草是常见的中药，具有清热凉血、活血解毒、透疹消疮的功效。紫草相关制剂在治疗肛周湿疹方面应用较多，具有一定的临床意义。文章通过回顾肛周湿疹的中西医发病机制，并对紫草在治疗肛周湿疹的作用机制进行归纳总结，以期能更好地指导临床治疗。Perianal eczema is a chronic allergic and non-communicable disease, which is a common skin disease around the anus. It has the characteristics of a long course and easy recurrence. Lithospermum erythrorhizon Siebold & Zucc. is a common traditional Chinese medicine that has the effects of clearing heat, cooling blood, promoting blood circulation, detoxifying, and clearing rashes and sores. Lithospermum erythrorhizon Siebold & Zucc. related preparations are widely used in the treatment of perianal eczema and have certain clinical significance. This article reviews the pathogenesis of perianal eczema in both traditional Chinese and Western medicine and summarizes the mechanism of action of Lithospermum erythrorhizon Siebold & Zucc. in treating perianal eczema, in order to better guide clinical treatment.