Kidneys Toxicity and Biodistribution of Albumin-Based Gold and Silver Nanoclusters

The identified renal toxicity linked to BSA-AgNCs, despite their lower kidney accumulation than BSA-AuNCs, illuminates the intricate interplay between nanoparticle biodistribution and toxicity. This underscores the significance of considering the core metal type in nanoparticle design and evaluation. Further investigation is needed to clarify the underlying molecular mechanisms of the observed biodistribution and toxicity.

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Publication Details

Journal
Current Drug Delivery
Published
2025-04-09
DOI
https://doi.org/10.2174/0115672018369974250321004041
Primary Topic
Nanocluster Synthesis and Applications
Type
article
Field-Weighted Citation Impact
0.00
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article

Kidneys Toxicity and Biodistribution of Albumin-Based Gold and Silver Nanoclusters

Maryam K. El-zubi, Mahmoud Y. Alkawareek, Nisreen Abu Shahin, Sameeha Alshelleh et al.
Current Drug Delivery
Nanocluster Synthesis and Applications
article

Kidneys Toxicity and Biodistribution of Albumin-Based Gold and Silver Nanoclusters

Maryam K. El-zubi, Mahmoud Y. Alkawareek, Nisreen Abu Shahin, Sameeha Alshelleh, Hussein Alhawari, Rashda Abbasi, Karem H. Alzoubi, Alaaldin M. Alkilany, Rania Mahafdeh
article en

Abstract

The identified renal toxicity linked to BSA-AgNCs, despite their lower kidney accumulation than BSA-AuNCs, illuminates the intricate interplay between nanoparticle biodistribution and toxicity. This underscores the significance of considering the core metal type in nanoparticle design and evaluation. Further investigation is needed to clarify the underlying molecular mechanisms of the observed biodistribution and toxicity.

Current Drug DeliveryVol. 22
University of Jordan (JO), Jordan University of Science and Technology (JO), Jadara University (JO), University of Sharjah (AE), Qatar University (QA)
Clean water and sanitation
Openalex Percentile: Top 95%
Nanocluster Synthesis and Applications
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Kidneys Toxicity and Biodistribution of Albumin-Based Gold and Silver Nanoclusters — Maryam K. El-zubi, Mahmoud Y. Alkawareek, et al. · Current Drug Delivery (2025) | TGRS Research Map | TGRS