Analysis of the Relationship Between NLRP3 and Alzheimer's Disease in Oligodendrocytes based on Bioinformatics and In Vitro Experiments

This study corroborates the high expression of NLRP3 in AD and its close relationship with the disease through integrated bioinformatics analysis and molecular biology experiments. Furthermore, the diagnostic model constructed based on the five key genes-PANX1, APP, P2RX7, MEFV, and NLRP3-not only provides a robust tool for early diagnosis of AD but also offers new insights for the development of treatment targets for AD.