Efficacy of Cooling Blankets and Cold Fluid Infusions in Classic Heatstroke Treatment: A Controlled Study in Rats

Cooling methods differ in effectiveness and impact on inflammation and organ function. While cooling blankets demonstrate limited therapeutic efficacy and potential risks when used in isolation, rapid cold fluid infusion emerges as the preferred cooling modality by preserving cardiac structure and renal function while attenuating systemic inflammation. Early rapid cooling improves organ function and prognosis in classic heatstroke rats. Proper cooling methods are crucial for effective heatstroke management, reducing organ damage, and improving survival rates.