Altered Brain Iron Depositions of Spinocerebellar Ataxia Type 3: From Pre‐Symptomatic to Symptomatic Stage
Our in vivo QSM evidence demonstrates disease-specific patterns for brain iron depositions in SCA3. Brain iron deposition abnormality is an early event of the SCA3's occurrence and development. The left SN might be a critical site for the disease's start and development.
Authors
- Jing Zhao (ORCID: https://orcid.org/0000-0002-9270-3250)
- Wenting Zeng (ORCID: https://orcid.org/0000-0003-2372-5066)
- Jiahui Liang (ORCID: https://orcid.org/0000-0001-9675-2677)
- Manshi Hu
- Haishan Qiu
- Chao Qiang Jiang (ORCID: https://orcid.org/0000-0001-6589-1068)
- Jianping Chu (ORCID: https://orcid.org/0000-0002-5526-9272)
- Runhua Sha
- Zihuan Huang (ORCID: https://orcid.org/0000-0002-1060-0785)
- Chao Wu (ORCID: https://orcid.org/0000-0002-0297-308X)
- Jiale Wu (ORCID: https://orcid.org/0009-0004-6252-1239)
Institutions
- Sun Yat-sen University (CN)
- Third Affiliated Hospital of Guangzhou Medical University (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
- Sun Yat-sen University Cancer Center (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- European Journal of Neurology
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1111/ene.70127
- Citations
- 3
- Primary Topic
- Genetic Neurodegenerative Diseases
- Type
- article
- Field-Weighted Citation Impact
- 2.73
Funders
- National Natural Science Foundation of China
- Basic and Applied Basic Research Foundation of Guangdong Province