Environmental toxicant 2,3,7,8-tetrachlorodibenzo-p-dioxin induces non-obstructive azoospermia: New insights from network toxicology, integrated machine learning, and biomolecular modeling
This study reveals the potential molecular mechanisms by which TCDD induces NOA, providing new targets for the development of diagnostic and therapeutic strategies.
Authors
- Guozheng Qin (ORCID: https://orcid.org/0000-0002-1808-8931)
- Xuyao Lin (ORCID: https://orcid.org/0000-0001-6122-0523)
- Zhuojun Yuan (ORCID: https://orcid.org/0000-0003-3117-7944)
- Shuai Chen (ORCID: https://orcid.org/0000-0003-0745-9546)
- Lei Xu (ORCID: https://orcid.org/0000-0003-4733-3761)
- Fugang Zhang
- Bin Huang (ORCID: https://orcid.org/0000-0002-5486-7924)
- Wei Fu
Institutions
- Guangzhou University of Chinese Medicine (CN)
- Yunnan University (CN)
- Yunnan Provincial Hospital of Traditional Chinese Medicine (CN)
- Yunnan University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Ecotoxicology and Environmental Safety
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1016/j.ecoenv.2025.118173
- Citations
- 4
- Primary Topic
- Toxic Organic Pollutants Impact
- Type
- article
- Field-Weighted Citation Impact
- 4.80