Gray matter structural alterations in first-episode drug-naïve adolescents with major depressive disorder: a comprehensive morphological analysis study
This study suggested that adolescent MDD had GM morphological abnormalities in the frontal-limbic, subcortical, perceptual network and midbrain regions, with some morphological abnormalities associated with disease duration and sex differences. These findings provide new insight into the neuroanatomical substrates underlying adolescent MDD.
Authors
- Baolin Wu (ORCID: https://orcid.org/0000-0003-4574-9747)
- Baoshuai Zhang
- Zhiyun Jia (ORCID: https://orcid.org/0000-0003-1886-5654)
- Lihua Qiu (ORCID: https://orcid.org/0000-0001-8045-3912)
- Qiyong Gong (ORCID: https://orcid.org/0000-0002-5912-4871)
- Andrea Mechelli (ORCID: https://orcid.org/0000-0002-6770-2934)
- Hongsheng Xie (ORCID: https://orcid.org/0000-0001-6952-0184)
- Ziru Zhao (ORCID: https://orcid.org/0009-0006-2301-4298)
- Xun Zhang (ORCID: https://orcid.org/0009-0008-6567-6702)
- Ruoqiu Gan
- Yi-Xuan Ling
Institutions
- King's College London (GB)
- Xiamen University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
- Second People’s Hospital of Yibin (CN)
Publication Details
- Journal
- Psychological Medicine
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1017/s0033291725000790
- Citations
- 5
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 7.16
Funders
- National Natural Science Foundation of China
- Sichuan University
- Natural Science Foundation of Sichuan Province
- West China Hospital, Sichuan University