Associations of polygenic risk score, environmental factors, and their interactions with the risk of schizophrenia spectrum disorders
Our findings suggest that the use of aggregate scores for genetic and environmental measures, PRS-SZ and K-PERS-I, can more accurately predict case-control status, and specific environmental measures may be more suitable for the exploration of GEIs.
Authors
- Young‐Chul Chung (ORCID: https://orcid.org/0000-0001-9491-1822)
- Seunghwan Park (ORCID: https://orcid.org/0000-0001-7753-085X)
- Hyojeong Seo
- Thi-Hung Le (ORCID: https://orcid.org/0000-0003-4163-3798)
- Wonil Chung (ORCID: https://orcid.org/0000-0002-5766-6247)
- Chaeyeong Kang
- Fatima Zahra Rami (ORCID: https://orcid.org/0000-0003-1706-6113)
- Seunghee Won (ORCID: https://orcid.org/0000-0002-4858-6173)
- Ling Li (ORCID: https://orcid.org/0000-0003-2471-0181)
- Sung‐Wan Kim (ORCID: https://orcid.org/0000-0002-6739-2163)
Institutions
- Harvard University (US)
- Soongsil University (KR)
- Kyungpook National University (KR)
- Chonnam National University Hospital (KR)
- Jeonbuk National University Hospital (KR)
- Jeonbuk National University (KR)
Publication Details
- Journal
- Psychological Medicine
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1017/s0033291725000753
- Citations
- 1
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 1.82