Palladium/norbornene cooperative catalysis triple functionalization: carbamoylation/double-annulation of (hetero)aryl iodides
A novel Pd/NBE-catalyzed intermolecular dehydrobicyclization of heteroaryl iodides for the synthesis of polycyclic nitrogen-containing heterocycles is reported. In this work, the <i>N</i>-protected aryl carbamoyl chloride serves as a source of acylation. The products resulting from the direct C-H functionalization of heteroaryl iodides are smoothly obtained without catalyst poisoning by heteroatoms.
Authors
- Yufan Yang (ORCID: https://orcid.org/0000-0001-6148-8570)
- Jin‐Heng Li (ORCID: https://orcid.org/0000-0001-7215-7152)
- Yanping Zhu (ORCID: https://orcid.org/0000-0003-1666-1850)
- Yuanyuan Sun (ORCID: https://orcid.org/0000-0002-1602-3050)
- Fengyu Zhang (ORCID: https://orcid.org/0000-0002-1418-0626)
- Yating Wang (ORCID: https://orcid.org/0000-0003-1126-1575)
- Yanmei Chen (ORCID: https://orcid.org/0000-0001-9154-2224)
- Jijing Zhao
- Yi-Xin Chai
Institutions
- Huanggang Normal University (CN)
- Qingdao University (CN)
- Qingdao University of Science and Technology (CN)
- Yantai University (CN)
Publication Details
- Journal
- Chemical Communications
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5cc00294j
- Primary Topic
- Catalytic C–H Functionalization Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.00