Clinicomolecular Profile and Efficacy of Human Epidermal Growth Factor Receptor 2 (HER2)-Targeted Therapy for <i>HER2</i> -Amplified Advanced Biliary Tract Cancer

<i>HER2</i> amplification was found in 10% of advanced BTC and was not identified as an independent prognostic factor for OS. Patients with <i>HER2</i>-amplified BTC derive significant benefit from HER2-targeted therapy.

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Publication Details

Journal
JCO Precision Oncology
Published
2025-04-01
DOI
https://doi.org/10.1200/po-24-00718
Citations
2
Primary Topic
Cholangiocarcinoma and Gallbladder Cancer Studies
Type
article
Field-Weighted Citation Impact
4.01
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article

Clinicomolecular Profile and Efficacy of Human Epidermal Growth Factor Receptor 2 (HER2)-Targeted Therapy for HER2 -Amplified Advanced Biliary Tract Cancer

Chigusa Morizane, John H. Strickler, Yoshiaki Nakamura, Masafumi Ikeda et al.
2 citations
JCO Precision Oncology
Cholangiocarcinoma and Gallbladder Cancer Studies
4.01
article

Clinicomolecular Profile and Efficacy of Human Epidermal Growth Factor Receptor 2 (HER2)-Targeted Therapy for HER2 -Amplified Advanced Biliary Tract Cancer

Chigusa Morizane, John H. Strickler, Yoshiaki Nakamura, Masafumi Ikeda, Kanae Inoue, Yasuyuki Kawamoto, Masayuki Furukawa, Binbin Zheng-Lin, Hideaki Bando, Shinji Itoh, Makoto Ueno, Bennett Adam Caughey, Takao Fujisawa, Takeshi Kajiwara, Taroh Satoh, Takayuki Yoshino, Kumiko Umemoto, Nobumasa Mizuno, Tanios Bekaii‐Saab, Kentaro Sudo
article en
2 citations

Abstract

<i>HER2</i> amplification was found in 10% of advanced BTC and was not identified as an independent prognostic factor for OS. Patients with <i>HER2</i>-amplified BTC derive significant benefit from HER2-targeted therapy.

JCO Precision OncologyVol. 9(9)
Kyushu University (JP), St. Marianna University School of Medicine (JP), Kanagawa Prefectural Hospital Organization (JP), Massachusetts General Hospital (US), National Hospital Organization Kyushu Cancer Center (JP), Chiba Cancer Center (JP), Duke Medical Center (US), Mayo Clinic Hospital (US), Aichi Cancer Center (JP), Shikoku Cancer Center (JP), Hokkaido University Hospital (JP), National Cancer Center Hospital East (JP), Osaka University Hospital (JP), Kanagawa Cancer Center
Openalex Percentile: Top 8%
Cholangiocarcinoma and Gallbladder Cancer Studies
4.01
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