Low Levels of Postvaccination Hemagglutination Inhibition Antibodies and Their Correlation With Influenza Protection Among Healthcare Workers During the 2024–2025 A/H1N1 Outbreak in Japan
After a prolonged period without a major influenza epidemic, HI titers against A/H1N1 were extremely low in vaccinated healthcare workers. Nonetheless, higher postvaccination HI titers, even at relatively low levels, were associated with protection, supporting the benefit of vaccines.
Authors
- Shohei Yamamoto (ORCID: https://orcid.org/0000-0001-6503-8577)
- Junko S. Takeuchi (ORCID: https://orcid.org/0000-0002-4844-9013)
- Tetsuya Mizoue (ORCID: https://orcid.org/0000-0002-1198-2228)
- Wataru Sugiura (ORCID: https://orcid.org/0000-0002-3132-0918)
- Mugen Ujiie (ORCID: https://orcid.org/0000-0001-8150-075X)
- Maki Konishi (ORCID: https://orcid.org/0009-0009-6118-4513)
- Norio Ohmagari (ORCID: https://orcid.org/0000-0002-4622-8970)
- Kumi Horii
Institutions
- Institute for Security Studies (KE)
- National Center for Global Health and Medicine (JP)
Publication Details
- Journal
- The Journal of Infectious Diseases
- Published
- 2025-04-09
- DOI
- https://doi.org/10.1093/infdis/jiaf183
- Citations
- 1
- Primary Topic
- Influenza Virus Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.35