Clinical and Microbiologic Outcomes of Antifungal Lock-based Catheter Salvage in Pediatric Candidal CLABSI
We report a retrospective review of pediatric candidal central line-associated bloodstream infections (N = 145) with antifungal lock therapy-based catheter salvage. Rates of recurrence (6%) and mortality (5%) were low at 28 days. At 1 year, earlier catheter removal was associated with lower recurrence rates (21% vs. 45%, P = 0.005), but no significant difference in mortality (13% vs. 5%).
Authors
- Andrew Nowalk (ORCID: https://orcid.org/0000-0002-1374-3167)
- Lorne W. Walker (ORCID: https://orcid.org/0000-0002-2500-0504)
Institutions
- Oregon Health & Science University (US)
- Children's Hospital of Pittsburgh (US)
- Pediatric Infectious Diseases Society (US)
Publication Details
- Journal
- The Pediatric Infectious Disease Journal
- Published
- 2025-04-03
- DOI
- https://doi.org/10.1097/inf.0000000000004820
- Primary Topic
- Central Venous Catheters and Hemodialysis
- Type
- article
- Field-Weighted Citation Impact
- 0.00