Rare Presentation of Rituximab-induced Interstitial Lung Disease in a Patient with Pemphigus Vulgaris.

A 42-year-old female with a history of pemphigus vulgaris was started on rituximab after an inadequate response to corticosteroids. One month following the second cycle of rituximab, she developed acute interstitial pneumonia, which was linked to rituximab since a thorough workup revealed no evidence of an infectious cause. We initiated her on broad-spectrum intravenous (IV) antibiotics and antifungals, but the patient responded significantly to pulse methylprednisolone therapy.

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Publication Details

Journal
PubMed
Published
2025-04-01
DOI
https://doi.org/10.59556/japi.73.0916
Citations
1
Primary Topic
Autoimmune Bullous Skin Diseases
Type
article
Field-Weighted Citation Impact
1.47
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article

Rare Presentation of Rituximab-induced Interstitial Lung Disease in a Patient with Pemphigus Vulgaris.

Mario Mekhail, R. Bhalla, Alla Sai Santhosha Mrudula, Kattamreddy Ananth Rupesh et al.
1 citations
PubMed
Autoimmune Bullous Skin Diseases
1.47
article

Rare Presentation of Rituximab-induced Interstitial Lung Disease in a Patient with Pemphigus Vulgaris.

Mario Mekhail, R. Bhalla, Alla Sai Santhosha Mrudula, Kattamreddy Ananth Rupesh, Srija Sirineni, Pravin Panditrao Kalyankar, Abhinav Vulisha, Deekshitha Alla, Nikhil Gupta
article en
1 citations

Abstract

A 42-year-old female with a history of pemphigus vulgaris was started on rituximab after an inadequate response to corticosteroids. One month following the second cycle of rituximab, she developed acute interstitial pneumonia, which was linked to rituximab since a thorough workup revealed no evidence of an infectious cause. We initiated her on broad-spectrum intravenous (IV) antibiotics and antifungals, but the patient responded significantly to pulse methylprednisolone therapy.

PubMedVol. 73(4)
Andhra University (IN), Texas Tech University (US), Gandhi Medical College & Hospital (IN), The University of Texas at El Paso (US), Fortis Escorts Hospital (IN), New York University Langone Orthopedic Hospital (US), Osmania Medical College (IN)
Good health and well-being
Openalex Percentile: Top 21%
Autoimmune Bullous Skin Diseases
1.47
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