Ovarian Activation Surgical Techniques for Women with Premature Ovarian Insufficiency or Poor Ovarian Response: A Systematic Review.
Ovarian fragmentation (OF) appears to be a promising method for treating POI, although large sample randomized controlled trials (RCTs) are necessary to confirm this hypothesis. Regarding POR, surgical techniques do not improve IVF outcomes, and thus should not be proposed, although they may lead to a slight increase in ovarian reserve markers as compared with before treatment. Both clinical and basic science studies are highly demanded to better understand the molecular mechanisms underlying some partially promising results, with the aim of improving currently available techniques.
Authors
- Antonio D’Amato (ORCID: https://orcid.org/0000-0001-6286-761X)
- Giuseppe D’Amato (ORCID: https://orcid.org/0009-0004-5712-3770)
- Giovanni Buzzaccarini (ORCID: https://orcid.org/0000-0002-9466-0178)
- Antonio Simone Laganà (ORCID: https://orcid.org/0000-0003-1543-2802)
- Amerigo Vitagliano (ORCID: https://orcid.org/0000-0002-2824-5435)
- Clementina Cantatore
- Andrea Etrusco (ORCID: https://orcid.org/0000-0001-7414-4224)
- Antonio Stanziano (ORCID: https://orcid.org/0000-0002-6257-5753)
- Anna Maria Caringella
Institutions
- Vita-Salute San Raffaele University (IT)
- Azienda Ospedaliera Universitaria Policlinico "Paolo Giaccone" di Palermo (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- University of Bari Aldo Moro (IT)
- University of Palermo (IT)
Publication Details
- Journal
- PubMed
- Published
- 2025-03-11
- DOI
- https://doi.org/10.22074/ijfs.2024.2021822.1622
- Primary Topic
- Ovarian function and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00