Polypharmacy and Mild Cognitive Impairment in Older Adults: A 3-year Study of DO-HEALTH
Our findings suggest that MCI is more prevalent in older adults with polypharmacy compared with those without polypharmacy. Although polypharmacy was associated with MCI at baseline and over 3 years, these associations were attenuated by mental health and multimorbidity, suggesting that mental health and multimorbidity contribute to both polypharmacy and MCI.
Authors
- Tatjana Meyer-Heim
- Angélique Sadlon (ORCID: https://orcid.org/0000-0002-9316-4113)
- Heike A. Bischoff‐Ferrari (ORCID: https://orcid.org/0000-0002-4554-658X)
- Klaus Baumann (ORCID: https://orcid.org/0000-0001-5333-9823)
- Adrian Egli (ORCID: https://orcid.org/0000-0002-3564-8603)
- Gregor Freystaetter (ORCID: https://orcid.org/0000-0003-4539-5627)
- Caroline de Godoi Rezende Costa Molino (ORCID: https://orcid.org/0000-0001-6925-1201)
- Reto W. Kressig (ORCID: https://orcid.org/0000-0002-3215-7681)
- Stephanie Gaengler
Institutions
- University of Zurich (CH)
- University Hospital of Zurich (CH)
- Felix Platter-Hospital (CH)
Publication Details
- Journal
- Journal of the American Medical Directors Association
- Published
- 2025-04-19
- DOI
- https://doi.org/10.1016/j.jamda.2025.105586
- Citations
- 2
- Primary Topic
- Pharmaceutical Practices and Patient Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 2.45