Dynamic Regulation of CYP19A1 Promoter Region under Control of CREB Family Members in Endometrial Tissues of Women with Endometriosis: A Case-Control Study.
The overexpression of <i>CREB, CREM,</i> and <i>CRTC2</i> in the endometriotic tissue samples and decreased binding of ICER to the <i>CYP19A1</i> prompter II in ectopic and eutopic samples may contribute to the pathogenesis of endometriosis via their regulatory role in the expression of estrogen biosynthesis enzymes.
Authors
- Elham Amirchaghmaghi
- Maryam Shahhoseini (ORCID: https://orcid.org/0000-0002-9021-6408)
- Fariba Ramezanali (ORCID: https://orcid.org/0000-0002-8506-4315)
- Ameneh Saadat Varnosfaderani
- Shadi Kalantari
Institutions
- University of Science and Culture (IR)
- Royan Institute (IR)
- Academic Center for Education, Culture and Research (IR)
Publication Details
- Journal
- PubMed
- Published
- 2025-03-11
- DOI
- https://doi.org/10.22074/ijfs.2024.2026438.1659
- Citations
- 2
- Primary Topic
- Endometriosis Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 3.40
Funders
- Royan Institute