Risk factors associated with gestational transient thyrotoxicosis and their effects on the pregnancy course

The study included 50 pregnant women who met the inclusion criteria and whose data could be accessed. Two pregnant women were diagnosed with gestational diabetes, and two pregnancies resulted in abortion. We observed that thyroid-stimulating hormone levels normalized to euthyroid values at a mean gestational age of 18.3 ± 3.7 weeks. The mean gestational age at birth was 38 ± 1.8 weeks. The frequency of preterm labor, defined as delivery before 37 weeks, was 10% (n = 5). Sinus rhythm was observed in 87% of the electrocardiograms obtained during thyrotoxicosis, while sinus tachycardia was detected in four and sinus arrhythmia in two cases. Thyroid nodules were observed in 23 (47.9%) of 48 cases in which ultrasonography was performed during thyrotoxicosis. Discussion: This retrospective study, including 50 pregnant women with gestational transient thyrotoxicosis, found no increase in the rate of serious obstetric complications such as eclampsia/preeclampsia, gestational diabetes, preterm labor, or abortion. Notably, in a detailed examination of electrocardiograms, which has not been done in previous studies, we did not detect any serious, life-threatening arrhythmias, although tachycardia was observed.

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Publication Details

Journal
Archives of Endocrinology and Metabolism
Published
2025-01-01
DOI
https://doi.org/10.20945/2359-4292-2024-0129
Primary Topic
Thyroid Disorders and Treatments
Type
article
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article

Risk factors associated with gestational transient thyrotoxicosis and their effects on the pregnancy course

Bağdagül Yüksel Güler, Cem Haymana, İbrahim Demirci, Alper Sönmez et al.
Archives of Endocrinology and Metabolism
Thyroid Disorders and Treatments
article

Risk factors associated with gestational transient thyrotoxicosis and their effects on the pregnancy course

Bağdagül Yüksel Güler, Cem Haymana, İbrahim Demirci, Alper Sönmez, Ahmet Faruk Yagci
article en

Abstract

The study included 50 pregnant women who met the inclusion criteria and whose data could be accessed. Two pregnant women were diagnosed with gestational diabetes, and two pregnancies resulted in abortion. We observed that thyroid-stimulating hormone levels normalized to euthyroid values at a mean gestational age of 18.3 ± 3.7 weeks. The mean gestational age at birth was 38 ± 1.8 weeks. The frequency of preterm labor, defined as delivery before 37 weeks, was 10% (n = 5). Sinus rhythm was observed in 87% of the electrocardiograms obtained during thyrotoxicosis, while sinus tachycardia was detected in four and sinus arrhythmia in two cases. Thyroid nodules were observed in 23 (47.9%) of 48 cases in which ultrasonography was performed during thyrotoxicosis. Discussion: This retrospective study, including 50 pregnant women with gestational transient thyrotoxicosis, found no increase in the rate of serious obstetric complications such as eclampsia/preeclampsia, gestational diabetes, preterm labor, or abortion. Notably, in a detailed examination of electrocardiograms, which has not been done in previous studies, we did not detect any serious, life-threatening arrhythmias, although tachycardia was observed.

Archives of Endocrinology and MetabolismVol. 69(2)
Ministry of Health (TR), Turkish Armed Forces (TR), Gülhane Askerî Tıp Akademisi (TR), Güven Hospital (TR), Education Training And Research (US), Sağlık Bilimleri Üniversitesi (TR), University of Health Sciences Antigua (AG)
Good health and well-being
Openalex Percentile: Top 90%
Thyroid Disorders and Treatments
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