Dihydromyricetin alleviates ETEC K88-induced intestinal inflammatory injury by inhibiting quorum sensing-related virulence factors
DMY can inhibit the AI-2 QS and virulence factor expression, thereby attenuating the virulence of ETEC and alleviating intestinal inflammatory damage in ETEC K88-challenged mice. This study indicated that DMY has the potential to be a promising antivirulence agent for combating ETEC infection.
Authors
- Yaqian Shi (ORCID: https://orcid.org/0000-0002-5480-2776)
- Zhongyuan Wu (ORCID: https://orcid.org/0000-0003-3240-6032)
- Yinsheng Qiu
- Chun Ye
- Jin Liu (ORCID: https://orcid.org/0000-0002-6485-1985)
- Hualin Zhou
Institutions
- Wuhan Polytechnic University (CN)
- Hubei University of Arts and Science (CN)
- Xiangyang Central Hospital (CN)
Publication Details
- Journal
- BMC Microbiology
- Published
- 2025-04-09
- DOI
- https://doi.org/10.1186/s12866-025-03879-8
- Citations
- 2
- Primary Topic
- Mycobacterium research and diagnosis
- Type
- article
- Field-Weighted Citation Impact
- 2.71
Funders
- National Natural Science Foundation of China