Resolution of MALDI-TOF compared to whole genome sequencing for identification of Bacillus species isolated from cleanrooms at NASA Johnson Space Center
Since MALDI-TOF MS costs less than whole genome sequencing and offers a throughput of hundreds of isolates per hour, this approach appears to offer a cost-efficient option for identifying <i>Bacillus</i> species, and related microbes, isolated during routine monitoring of cleanrooms and similar built environments.
Authors
- Michael G. LaMontagne
- Christian L. Castro (ORCID: https://orcid.org/0000-0003-2271-0073)
- A. B. Regberg (ORCID: https://orcid.org/0000-0002-9121-2118)
- Farnaz Mazhari
Institutions
- Johnson Space Center (US)
- University of Houston - Clear Lake (US)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-04-09
- DOI
- https://doi.org/10.3389/fmicb.2025.1499516
- Citations
- 2
- Primary Topic
- Bacterial Identification and Susceptibility Testing
- Type
- article
- Field-Weighted Citation Impact
- 2.64
Funders
- National Aeronautics and Space Administration
- Johnson Space Center
- Science Mission Directorate