The FUSION Study: compatibility of antibiotics with commonly used medication infusions in a paediatric intensive care unit
This study describes the favourable compatibility of fentanyl, morphine and vancomycin admixtures with the study drugs. It highlights the incompatibility of midazolam when co-infused with beta-lactam antibiotics. Clinicians must exercise caution when co-administering prolonged infusions of antibiotics to minimise the risk of antibiotic ineffectiveness.
Authors
- Menino Osbert Cotta
- Luregn J. Schlapbach (ORCID: https://orcid.org/0000-0003-2281-2598)
- Hayoung Won (ORCID: https://orcid.org/0000-0002-9248-5134)
- Jason A. Roberts (ORCID: https://orcid.org/0000-0001-6218-435X)
- Sonya Stacey (ORCID: https://orcid.org/0000-0003-2535-9688)
- Steven C. Wallis (ORCID: https://orcid.org/0000-0002-2392-9854)
- Fekade B. Sime (ORCID: https://orcid.org/0000-0003-4061-2063)
- Sainath Raman (ORCID: https://orcid.org/0000-0002-0152-9980)
- Dušan Marjanović
- Quyen Tu (ORCID: https://orcid.org/0000-0002-1910-1069)
Institutions
- Children's Medical Research Institute (AU)
- The University of Queensland (AU)
- Royal Brisbane and Women's Hospital (AU)
- Metro South Health (AU)
- Children’s Health Queensland Hospital and Health Service (AU)
- University Children's Hospital Zurich (CH)
- Children's Health Queensland Hospital and Health Service (AU)
- Université de Nîmes (FR)
Publication Details
- Journal
- European Journal of Hospital Pharmacy
- Published
- 2025-04-09
- DOI
- https://doi.org/10.1136/ejhpharm-2024-004450
- Citations
- 5
- Primary Topic
- Patient Safety and Medication Errors
- Type
- article
- Field-Weighted Citation Impact
- 12.58