Temporal Shift When Comparing Contrast-Agent Concentration Curves Estimated Using Quantitative Susceptibility Mapping (QSM) and ΔR2*: The Association Between Vortex Parameters and Oxygen Extraction Fraction
GRE-based GM vortex parameters correlated significantly with whole-brain OEF. In agreement with expectations, the corresponding AIF data, representing high fractions of arterial blood, showed no significant correlation. Novel parameters, based solely on standard GRE protocols, are of relevance to investigate, considering that GRE-based DSC-MRI is very common in brain tumour applications.
Authors
- Linda Knutsson (ORCID: https://orcid.org/0000-0002-4263-113X)
- Emelie Lind (ORCID: https://orcid.org/0000-0002-1968-9093)
- Anna Lundberg (ORCID: https://orcid.org/0000-0001-9509-7340)
- Ronnie Wirestam (ORCID: https://orcid.org/0000-0003-2628-0760)
Institutions
- Kennedy Krieger Institute (US)
- Johns Hopkins University (US)
- Lund University (SE)
- Johns Hopkins Medicine (US)
- Skåne University Hospital (SE)
Publication Details
- Journal
- Tomography
- Published
- 2025-04-09
- DOI
- https://doi.org/10.3390/tomography11040046
- Primary Topic
- Metabolomics and Mass Spectrometry Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Crafoordska Stiftelsen
- Hjärnfonden
- Vetenskapsrådet