Hidden in <scp>CAKUT</scp>: Post‐Transplant Diagnosis of Primary Hyperoxaluria Type 1 and Rescue Management Using Lumasiran
This case underscores the importance of maintaining a high index of suspicion for PH1 in patients with congenital anomalies of the kidney and urinary tract (CAKUT) or unexplained end-stage kidney disease (ESKD) cases, even post-transplantation. It also demonstrates the potential efficacy of lumasiran in managing PH1 post-transplantation when combined with intensive hemodialysis and supportive care. However, more studies with prolonged follow-up periods are necessary to establish the long-term efficacy and safety of lumasiran in the treatment of PH1 without the requirement for liver transplantation.
Authors
- Najla Aldaoud (ORCID: https://orcid.org/0000-0003-4451-1198)
- Alanoud Alshami (ORCID: https://orcid.org/0000-0002-6199-5174)
- Ammar Hamed
- Ahmed Y. Azzam (ORCID: https://orcid.org/0000-0002-4256-0159)
- Hebatallah Bahbah
Institutions
- Jordan University of Science and Technology (JO)
- King Fahad Specialist Hospital (SA)
Publication Details
- Journal
- Pediatric Transplantation
- Published
- 2025-04-09
- DOI
- https://doi.org/10.1111/petr.70079
- Citations
- 1
- Primary Topic
- Kidney Stones and Urolithiasis Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.52