The Spectrum of Macular Ischemia in West Nile Virus Chorioretinitis
This case represents the first documented use of RT-PCR analysis of aqueous humor to confirm WNV infection, providing a novel diagnostic approach for atypical presentations. Multimodal imaging, including SD-OCT and OCT-A, revealed multilevel ischemic retinal damage and highlighted the acute and chronic lesions. These findings underscore the importance of advanced imaging and molecular diagnostics in identifying and managing ocular manifestations of WNV.
Authors
- Jacopo Mariotti (ORCID: https://orcid.org/0000-0001-6528-9296)
- Sara Racca (ORCID: https://orcid.org/0000-0002-2389-3716)
- Maria Vittoria Cicinelli (ORCID: https://orcid.org/0000-0003-2938-0409)
- Stéfania Bramanti (ORCID: https://orcid.org/0000-0002-4117-7991)
- Daniele Mannina (ORCID: https://orcid.org/0000-0002-1378-6896)
- Elisabetta Miserocchi (ORCID: https://orcid.org/0000-0003-2989-6712)
- Daniela Taurino (ORCID: https://orcid.org/0009-0009-0276-8295)
- Barbara Sarina (ORCID: https://orcid.org/0000-0001-8138-7988)
- Soufiane Bousyf
Institutions
- Humanitas University (IT)
- Vita-Salute San Raffaele University (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- IRCCS Humanitas Research Hospital (IT)
- Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele (IT)
Publication Details
- Journal
- Ocular Immunology and Inflammation
- Published
- 2025-04-09
- DOI
- https://doi.org/10.1080/09273948.2025.2482684
- Primary Topic
- Mosquito-borne diseases and control
- Type
- article
- Field-Weighted Citation Impact
- 0.00