Expression of costimulatory molecule CD70 is prognostic in small cell lung cancer
CD70, B-cell density and the presence of TLSs, but not CD27, emerged as a significant prognostic biomarker for OS in surgically treated SCLC, suggesting its potential as a therapeutic target.
Authors
- Kenan Aloss (ORCID: https://orcid.org/0000-0003-4806-7477)
- Balázs B. Lőrincz
- Péter Takács (ORCID: https://orcid.org/0000-0002-0078-5763)
- Imre Vörös
- David Dora (ORCID: https://orcid.org/0000-0002-3138-8816)
- Zoltán V. Varga (ORCID: https://orcid.org/0000-0002-4889-3376)
- Zsolt Megyesfalvi (ORCID: https://orcid.org/0000-0001-8552-6500)
- Balázs Döme (ORCID: https://orcid.org/0000-0001-8799-8624)
- Christopher J. Rivard
- Zoltán Lohinai (ORCID: https://orcid.org/0000-0002-6442-9530)
- Syeda Mahak Zahra Bokhari (ORCID: https://orcid.org/0000-0002-6812-374X)
- Fred R. Hirsch (ORCID: https://orcid.org/0000-0002-6885-1894)
- Ágnes Paál
- Hui Yu (ORCID: https://orcid.org/0000-0003-3103-9672)
- Anikó Görbe (ORCID: https://orcid.org/0000-0003-4908-1094)
- D. Dobos
- Gergely Pallag
Institutions
- Semmelweis University (HU)
- Mount Sinai Health System (US)
- Comprehensive Cancer Center Vienna (AT)
- National Institute of Oncology (HU)
- Montavid Thermodynamic Research Group (HU)
- Országos Korányi Tbc és Pulmonológiai Intézet (HU)
- University of Colorado Anschutz Medical Campus (US)
Publication Details
- Journal
- Cancer Immunology Immunotherapy
- Published
- 2025-04-09
- DOI
- https://doi.org/10.1007/s00262-025-04006-2
- Primary Topic
- Lung Cancer Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- European Commission
- Semmelweis Egyetem
- Austrian Science Fund
- Hungarian Scientific Research Fund
- Magyar Tudományos Akadémia
- Innovációs és Technológiai Minisztérium
- Nemzeti Kutatási, Fejlesztési és Innovaciós Alap
- National Research, Development and Innovation Office