Molecular targeted maintenance therapy versus standard of care in advanced biliary cancer: an international, randomised, controlled, open-label, phase III umbrella trial (SAFIR-ABC10—Precision Medicine)
SAFIR-ABC10 is, to our knowledge, the first randomised, umbrella trial assessing the concept of precision medicine in ABC, the ideal setting for addressing this question with a high rate of targetable alterations.
Authors
- Ivan Borbath (ORCID: https://orcid.org/0000-0001-7598-214X)
- D. Couch
- James M. S. Wason (ORCID: https://orcid.org/0000-0002-4691-126X)
- David Malka (ORCID: https://orcid.org/0000-0002-7664-0130)
- Marisol Uribe Jiménez (ORCID: https://orcid.org/0000-0002-3322-265X)
- Andre Lopes (ORCID: https://orcid.org/0000-0002-1405-7337)
- Timon Vandamme (ORCID: https://orcid.org/0000-0003-3701-5305)
- Julien Edeline (ORCID: https://orcid.org/0000-0002-8289-7741)
- Inge De Bruyne
- Liesbeth Dewever
- Juan W. Valle (ORCID: https://orcid.org/0000-0002-1999-0863)
- John A. Bridgewater (ORCID: https://orcid.org/0000-0001-9186-1604)
- E. Ambrose
Institutions
- Cliniques Universitaires Saint-Luc (BE)
- Cancer Research UK (GB)
- London Cancer (GB)
- Institute Mutualiste Montsouris (FR)
- Centre Eugène Marquis (FR)
- The Christie NHS Foundation Trust (GB)
- Buildwise (BE)
- UniCancer Group (FR)
- Cholangiocarcinoma Foundation (US)
- University College London (GB)
- Newcastle University (GB)
Publication Details
- Journal
- ESMO Open
- Published
- 2025-04-09
- DOI
- https://doi.org/10.1016/j.esmoop.2025.104540
- Citations
- 8
- Primary Topic
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 16.05