Structural and functional tissue response to implants in patients with recurrent abdominal wall hernias in long-term period

Polypropylene and polyethylene terephthalate endoprostheses were subject to destruction over time (after 7 years in our study). Any implant causes persistent inflammation many years later. Desynchronization of inflammation and regeneration phases can lead to excessive connective tissue with its subsequent fibrous transformation and implant deformation in long-term period (up to 19 years).