A Thrombocytopenic Thrombotic Purpura in a Patient With a Metastatic HER2+ Breast Cancer: Description of a Case Report

Paraneoplastic (p) TTP is a rare syndrome characterized by an immune-induced, generalized microangiopathy associated with solid or hematological tumors. This case, reporting a patient with a metastatic HER2+ breast cancer and a pTTP, highlights the rarity of this entity, its difficult and challenging diagnosis, and the complexity of its management.

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Publication Details

Journal
Clinical Case Reports
Published
2025-04-01
DOI
https://doi.org/10.1002/ccr3.70395
Primary Topic
Complement system in diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

A Thrombocytopenic Thrombotic Purpura in a Patient With a Metastatic HER2+ Breast Cancer: Description of a Case Report

Francesca Plastino, Julie Egea, Paul Coppo, Pierre‐Olivier Legros et al.
Clinical Case Reports
Complement system in diseases
article

A Thrombocytopenic Thrombotic Purpura in a Patient With a Metastatic HER2+ Breast Cancer: Description of a Case Report

Francesca Plastino, Julie Egea, Paul Coppo, Pierre‐Olivier Legros, Raffaele Longo, Marco Campitiello, Romane Ribal, Alexandre Dadoun, Benjamin Savenkoff, Nathalie Marcon
article en

Abstract

Paraneoplastic (p) TTP is a rare syndrome characterized by an immune-induced, generalized microangiopathy associated with solid or hematological tumors. This case, reporting a patient with a metastatic HER2+ breast cancer and a pTTP, highlights the rarity of this entity, its difficult and challenging diagnosis, and the complexity of its management.

Clinical Case ReportsVol. 13(4)
Sorbonne Université (FR), Assistance Publique – Hôpitaux de Paris (FR), Hôpital Saint-Antoine (FR), Centre Hospitalier Régional de Metz-Thionville (FR)
Good health and well-being
Openalex Percentile: Top 92%
Complement system in diseases
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