Synthesis of Fused-Housane Derivatives via Intramolecular [2 + 2] Photocycloaddition
Herein, we describe a [2 + 2] photocycloaddition of cyclopropenes bearing a styryl group to prepare housane derivatives. The reaction occurs via selective excitation of the styrene fragment, enabling a completely stereoselective stepwise [2 + 2] cycloaddition. Fused-housane derivatives with an unprecedented substitution pattern are prepared in a simple manner using convenient visible light.
Authors
- R. Vicente (ORCID: https://orcid.org/0000-0002-3251-1820)
- Iratxe Barbolla (ORCID: https://orcid.org/0000-0002-4124-7697)
- Miguel A. Rodrı́guez (ORCID: https://orcid.org/0000-0003-0123-9905)
- David Suárez‐García
Institutions
- Universidad de Oviedo (ES)
- Universidad de La Rioja (ES)
- Consejo Nacional de Ciencia y Tecnología (PY)
- ORFEO-CINQA Research Network (ES)
Publication Details
- Journal
- Organic Letters
- Published
- 2025-04-09
- DOI
- https://doi.org/10.1021/acs.orglett.5c00468
- Citations
- 10
- Primary Topic
- Radical Photochemical Reactions
- Type
- article
- Field-Weighted Citation Impact
- 9.36
Funders
- Gobierno del Principado de Asturias
- Ministerio de Ciencia, Innovación y Universidades
- Agencia Estatal de Investigación