Perioperative Nitric Oxide Conditioning Reduces Acute Kidney Injury in Cardiac Surgery Patients with Chronic Kidney Disease (the DEFENDER Trial): A Randomized Controlled Trial
Perioperative NO administration in CKD patients undergoing cardiac surgery with cardiopulmonary bypass is safe, reduces the incidence of AKI, and slows the progression of renal dysfunction.
Authors
- Boris N. Kozlov (ORCID: https://orcid.org/0000-0002-0217-7737)
- Mark A. Tyo (ORCID: https://orcid.org/0000-0003-2672-6136)
- Igor V. Kravchenko (ORCID: https://orcid.org/0000-0003-0841-4673)
- Каменщиков Николай Олегович (ORCID: https://orcid.org/0000-0003-4289-4439)
- Lorenzo Berra (ORCID: https://orcid.org/0000-0003-2702-2093)
- Yu. K. Podoksenov (ORCID: https://orcid.org/0000-0002-8939-2340)
- А. М. Гусакова (ORCID: https://orcid.org/0000-0002-3147-3025)
Institutions
- Russian Academy of Sciences (RU)
- Harvard University (US)
- Massachusetts General Hospital (US)
- Tomsk National Research Medical Center (RU)
Publication Details
- Journal
- Anesthesiology
- Published
- 2025-04-09
- DOI
- https://doi.org/10.1097/aln.0000000000005494
- Citations
- 3
- Primary Topic
- Cardiac, Anesthesia and Surgical Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 4.16