A cohort study on the correlation between serum Klotho levels and all-cause mortality in American diabetic populations

Low levels of Klotho were found to be strongly associated with an increased risk of all-cause mortality in individuals with diabetes (Klotho levels < 829.138 pg/ml), and a nonlinear relationship was observed between these two variables. These associations were largely mediated by age.

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Publication Details

Journal
Diabetology & Metabolic Syndrome
Published
2025-04-09
DOI
https://doi.org/10.1186/s13098-025-01686-9
Primary Topic
Parathyroid Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

A cohort study on the correlation between serum Klotho levels and all-cause mortality in American diabetic populations

Yi‐Ying Lin, Jiaqi Chen, Kangxiang Wu, Jie Wang
Diabetology & Metabolic Syndrome
Parathyroid Disorders and Treatments
article

A cohort study on the correlation between serum Klotho levels and all-cause mortality in American diabetic populations

Yi‐Ying Lin, Jiaqi Chen, Kangxiang Wu, Jie Wang
article en

Abstract

Low levels of Klotho were found to be strongly associated with an increased risk of all-cause mortality in individuals with diabetes (Klotho levels < 829.138 pg/ml), and a nonlinear relationship was observed between these two variables. These associations were largely mediated by age.

Diabetology & Metabolic SyndromeVol. 17(1)
Wenzhou Medical University (CN), Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University (CN)
Good health and well-being
Openalex Percentile: Top 91%
Parathyroid Disorders and Treatments
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