Incidental Durotomy During Transforaminal Lumbar Interbody Fusion (TLIF) Surgery with Expandable Interbody Spacers: A Retrospective, Single-Center Analysis of Complications and Outcomes

Study DesignRetrospective cohort study.ObjectivesTo evaluate the frequency, risk factors, and impact of incidental durotomy on adverse events and outcomes after TLIF with expandable interbody spacers.MethodsWe reviewed 433 consecutive patients treated by TLIF using expandable titanium interbody implants (ALTERA®, Globus Medical Inc) on 538 levels between December 2018 and September 2023. Patients with incidental durotomy (ID) and cerebrospinal fluid leakage were compared to patients without ID, focusing on patient-specific and surgery-related factors, adverse events, clinical outcomes (MacNab criteria), and radiological outcomes at discharge, 3, and 12 months.ResultsThe ID rate was 9.0% (39/433 patients). Patients with ID had lower BMI (26.1 ± 5.2 vs 28.0 ± 5.3 kg/m<sup>2</sup>, <i>P</i> = .03), longer surgery duration (358 ± 132 vs 305 ± 128 minutes, <i>P</i> = .01), and extended hospital stays (14.7 ± 12.8 vs 10.9 ± 8.2 days, <i>P</i> < .01). More postoperative adverse events (51.3% vs 28.7%, <i>P</i> = .004) with higher severity (28.2% vs 13.2% moderate to severe, <i>P</i> = .019) occurred at discharge. No differences were found in outcomes at 3 or 12 months. ID patients showed higher risks for impaired wound healing (adjusted OR, 4.39; 95% CI, 1.90-10.2; <i>P</i> = .001) and pulmonary embolism (adjusted OR, 3.52; 95% CI, 1.13-10.9; <i>P</i> = .029).ConclusionsIncidental durotomy was associated with longer surgery time, hospital stays, and increased early postoperative complications. While not affecting mid-to-long-term outcomes, ID increased risks for wound healing difficulties and pulmonary embolisms.

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Journal
Global Spine Journal
Published
2025-04-08
DOI
https://doi.org/10.1177/21925682251332547
Primary Topic
Spine and Intervertebral Disc Pathology
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article
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article

Incidental Durotomy During Transforaminal Lumbar Interbody Fusion (TLIF) Surgery with Expandable Interbody Spacers: A Retrospective, Single-Center Analysis of Complications and Outcomes

Yesim Yildiz, Felix C. Stengel, Benjamin Martens, Daniele Gianoli et al.
Global Spine Journal
Spine and Intervertebral Disc Pathology
article

Incidental Durotomy During Transforaminal Lumbar Interbody Fusion (TLIF) Surgery with Expandable Interbody Spacers: A Retrospective, Single-Center Analysis of Complications and Outcomes

Yesim Yildiz, Felix C. Stengel, Benjamin Martens, Daniele Gianoli, Thomas Schöfl, Gregor Fischer, Nader Hejrati, Linda Bättig, Stefan Motov, Lorenzo Bertulli, Martin N. Stienen, Francis Kissling, Laurin Feuerstein
article en

Abstract

Study DesignRetrospective cohort study.ObjectivesTo evaluate the frequency, risk factors, and impact of incidental durotomy on adverse events and outcomes after TLIF with expandable interbody spacers.MethodsWe reviewed 433 consecutive patients treated by TLIF using expandable titanium interbody implants (ALTERA®, Globus Medical Inc) on 538 levels between December 2018 and September 2023. Patients with incidental durotomy (ID) and cerebrospinal fluid leakage were compared to patients without ID, focusing on patient-specific and surgery-related factors, adverse events, clinical outcomes (MacNab criteria), and radiological outcomes at discharge, 3, and 12 months.ResultsThe ID rate was 9.0% (39/433 patients). Patients with ID had lower BMI (26.1 ± 5.2 vs 28.0 ± 5.3 kg/m<sup>2</sup>, <i>P</i> = .03), longer surgery duration (358 ± 132 vs 305 ± 128 minutes, <i>P</i> = .01), and extended hospital stays (14.7 ± 12.8 vs 10.9 ± 8.2 days, <i>P</i> < .01). More postoperative adverse events (51.3% vs 28.7%, <i>P</i> = .004) with higher severity (28.2% vs 13.2% moderate to severe, <i>P</i> = .019) occurred at discharge. No differences were found in outcomes at 3 or 12 months. ID patients showed higher risks for impaired wound healing (adjusted OR, 4.39; 95% CI, 1.90-10.2; <i>P</i> = .001) and pulmonary embolism (adjusted OR, 3.52; 95% CI, 1.13-10.9; <i>P</i> = .029).ConclusionsIncidental durotomy was associated with longer surgery time, hospital stays, and increased early postoperative complications. While not affecting mid-to-long-term outcomes, ID increased risks for wound healing difficulties and pulmonary embolisms.

Global Spine JournalVol. 15(8)
University of St.Gallen (CH)
Good health and well-being
Openalex Percentile: Top 90%
Spine and Intervertebral Disc Pathology
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