Targeted metabolomics unravels the mechanism by phenylpropanoid-rich of the peel of Zea mays L. ameliorates metabolic disorders in diabetic mice through gut microbiota modulation
This work investigated the regulating effect of YMP on the liver glycolipid metabolism for the first time, and it also showed the underlying mechanism through gut microbiota. According to these studies, YMP has a lot of potential to be used as a supplemental treatment for complex metabolic illnesses like diabetes. It offered empirical support for the use of alternative medicine in the area to treat complex problems of glucose and lipid metabolism in diabetes.
Authors
- Guangtong Chen (ORCID: https://orcid.org/0000-0002-3274-9281)
- Yingjie He (ORCID: https://orcid.org/0000-0001-8361-2528)
- Bai Ling
- Yuru Yang
- Jinyan He (ORCID: https://orcid.org/0000-0002-6190-4535)
- Andong Wang (ORCID: https://orcid.org/0000-0003-2281-7946)
- Xiaotian Cheng
Institutions
- Xuzhou Medical College (CN)
- Nantong University (CN)
- Yancheng First People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-04-09
- DOI
- https://doi.org/10.3389/fphar.2025.1551713
- Citations
- 3
- Primary Topic
- GABA and Rice Research
- Type
- article
- Field-Weighted Citation Impact
- 5.25
Funders
- National Natural Science Foundation of China
- Government of Jiangsu Province
- Nantong University