Nucleus accumbens functional connectivity changes underlying alcohol expectancies in bipolar disorder and prospective alcohol outcomes: a within-subject randomized placebo-controlled alcohol administration fMRI study
Results suggest differences in placebo response in bipolar disorder, including distinct neural correlates, that may relate to prospective alcohol use/problems. Given the theoretical association between placebo response and self-reported alcohol expectancies, findings could open the door to interventions aimed at changing expectancies.
Authors
- Ansley Huffman (ORCID: https://orcid.org/0000-0003-3875-7482)
- Kim Fromme (ORCID: https://orcid.org/0000-0002-8530-2010)
- S.-H. Lee
- Elizabeth Lippard (ORCID: https://orcid.org/0000-0002-0528-3308)
- Dylan Kirsch (ORCID: https://orcid.org/0000-0001-9935-9635)
- Raquel Kosted
- Jorge Almeida (ORCID: https://orcid.org/0000-0002-1213-1986)
- Stephen M. Strakowski (ORCID: https://orcid.org/0000-0003-2837-6280)
- Nadia Bibb (ORCID: https://orcid.org/0000-0001-7111-2390)
- Vanessa Le
- Kaitlyn Meek
Institutions
- Indian School of Business (IN)
- University of California, Los Angeles (US)
- The University of Texas at Austin (US)
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- Frontiers in Neuroscience
- Published
- 2025-04-09
- DOI
- https://doi.org/10.3389/fnins.2025.1549295
- Citations
- 1
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.43
Funders
- University of Texas at Austin
- National Institute on Alcohol Abuse and Alcoholism