Population pharmacokinetics and dose optimization of voriconazole in patients with COVID-19-associated pulmonary aspergillosis

This study provides an evidence-based guide for voriconazole dosing adjustments in CAPA patients, particularly for those undergoing CRRT. The findings emphasize the importance of individualized dosing to improve therapeutic outcomes in this high-risk population.

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Publication Details

Journal
Frontiers in Pharmacology
Published
2025-04-09
DOI
https://doi.org/10.3389/fphar.2025.1554370
Citations
7
Primary Topic
Antifungal resistance and susceptibility
Type
article
Field-Weighted Citation Impact
9.77
Controls
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article

Population pharmacokinetics and dose optimization of voriconazole in patients with COVID-19-associated pulmonary aspergillosis

Yue Shen, Huaijun Zhu, Hui Wang, Jing Wang et al.
7 citations
Frontiers in Pharmacology
Antifungal resistance and susceptibility
9.77
article

Population pharmacokinetics and dose optimization of voriconazole in patients with COVID-19-associated pulmonary aspergillosis

Yue Shen, Huaijun Zhu, Hui Wang, Jing Wang, Xuemei Luo, Lu Jin
article en
7 citations

Abstract

This study provides an evidence-based guide for voriconazole dosing adjustments in CAPA patients, particularly for those undergoing CRRT. The findings emphasize the importance of individualized dosing to improve therapeutic outcomes in this high-risk population.

Frontiers in PharmacologyVol. 16
Nanjing Drum Tower Hospital (CN), First Affiliated Hospital of Xi'an Jiaotong University (CN)
Openalex Percentile: Top 2%
Antifungal resistance and susceptibility
9.77
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