Decoding the evolutionary history of ST30 Staphylococcus aureus: insights into a potentially silent MSSA bloodstream pathogen
Our study revises the evolutionary history of ST30 <i>S. aureus</i> uncovering critical pathoadaptive events that may explain its success. Additionally, our findings emphasize a neglected issue: the high prevalence of MSSA in hospital infections, particularly the silent circulation of TSST-1 producing strains, capable of causing severe infections. Robust surveillance studies to monitor these strains are crucial.
Authors
- Matheus Assis Côrtes Esteves
- Paul J. Planet (ORCID: https://orcid.org/0000-0003-0543-0539)
- Agnes Marie Sá Figueiredo (ORCID: https://orcid.org/0000-0001-8229-6957)
- Luís Guilherme de Araújo Longo
- Caroline Martini (ORCID: https://orcid.org/0000-0001-8637-6110)
- Alice Slotfeldt Viana (ORCID: https://orcid.org/0000-0003-0121-592X)
- Mariana Fernandes Carvalho (ORCID: https://orcid.org/0009-0004-2492-3317)
- Deborah Nascimento Santos Silva (ORCID: https://orcid.org/0000-0001-5540-5740)
- Adriana Lúcia Pires Ferreira (ORCID: https://orcid.org/0000-0001-9801-9401)
- Bernadete Teixeira Ferreira‐Carvalho
Institutions
- Universidade Federal do Rio de Janeiro (BR)
- Children's Hospital of Philadelphia (US)
- Universidade Federal Fluminense (BR)
- Universidade do Estado do Rio de Janeiro (BR)
- University of Pennsylvania (US)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-04-09
- DOI
- https://doi.org/10.3389/fmicb.2025.1522747
- Citations
- 3
- Primary Topic
- Antimicrobial Resistance in Staphylococcus
- Type
- article
- Field-Weighted Citation Impact
- 4.19
Funders
- Bill and Melinda Gates Foundation
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro