Genetic and clinical profile of high myopia patients with rhegmatogenous retinal detachment
RetNet genes are the predominant causative genes (18/40, 45.0%) in patients with high myopia and retinal detachment. The findings affirm that Stickler syndrome (15%) is a significant etiological factor for high myopia accompanied by retinal detachment. We recommend enhanced comprehensive systemic and ophthalmic examinations for patients with high myopia to enable early detection and prevention of retinal detachment.
Authors
- Yongchuan Liao (ORCID: https://orcid.org/0000-0003-3227-0489)
- Fanwen Jiang
- Zhuping Xu (ORCID: https://orcid.org/0000-0002-1270-9602)
- Hui Chen
- Lin Zhou (ORCID: https://orcid.org/0000-0003-2581-4345)
- Chun Zhang (ORCID: https://orcid.org/0000-0003-3565-8024)
- Jing Xiao
- Hui Jiang
- Farrukhjon Boboev
Institutions
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
Publication Details
- Journal
- Frontiers in Genetics
- Published
- 2025-04-09
- DOI
- https://doi.org/10.3389/fgene.2025.1485874
- Citations
- 1
- Primary Topic
- Retinal and Macular Surgery
- Type
- article
- Field-Weighted Citation Impact
- 1.36
Funders
- National Natural Science Foundation of China
- Sichuan University
- National Outstanding Youth Science Fund Project of National Natural Science Foundation of China
- West China Hospital, Sichuan University