A case report and literature review on giant tumefactive perivascular spaces

This study reports a rare GTPVS case, establishing diagnostic criteria, differential diagnosis, and management strategies. While asymptomatic cases require no treatment, hydrocephalus may necessitate surgery. Literature review suggests PVS dilation reflects glymphatic dysfunction, providing new pathophysiological insights. Further studies are needed to validate these findings due to the condition's rarity.

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Publication Details

Journal
Frontiers in Neuroscience
Published
2025-04-09
DOI
https://doi.org/10.3389/fnins.2025.1554910
Primary Topic
Cerebrospinal fluid and hydrocephalus
Type
article
Field-Weighted Citation Impact
0.00
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A case report and literature review on giant tumefactive perivascular spaces

Xiaoli Mai, Shuhan Liu, Chang Cheng, Ke Ma et al.
1 links
Frontiers in Neuroscience
Cerebrospinal fluid and hydrocephalus
article

A case report and literature review on giant tumefactive perivascular spaces

Xiaoli Mai, Shuhan Liu, Chang Cheng, Ke Ma, Yiqi Pan
article en

Abstract

This study reports a rare GTPVS case, establishing diagnostic criteria, differential diagnosis, and management strategies. While asymptomatic cases require no treatment, hydrocephalus may necessitate surgery. Literature review suggests PVS dilation reflects glymphatic dysfunction, providing new pathophysiological insights. Further studies are needed to validate these findings due to the condition's rarity.

Frontiers in NeuroscienceVol. 19
Xuzhou Medical College (CN), Nanjing Drum Tower Hospital (CN), Nanjing Medical University (CN)
Good health and well-being
Openalex Percentile: Top 91%
Cerebrospinal fluid and hydrocephalus
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