Exploring the role of LOX family in glioma progression and immune modulation

The LOX family is overexpressed in glioma and is associated with poor prognosis and altered immune infiltration patterns. These findings highlight the LOX family as a promising prognostic marker and therapeutic target, particularly for enhancing the effectiveness of immunotherapy in glioma treatment.

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Publication Details

Journal
Frontiers in Immunology
Published
2025-04-09
DOI
https://doi.org/10.3389/fimmu.2025.1512186
Citations
4
Primary Topic
Neuroinflammation and Neurodegeneration Mechanisms
Type
article
Field-Weighted Citation Impact
3.37
Controls
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article

Exploring the role of LOX family in glioma progression and immune modulation

Hengheng Zhang, Xiaolong Hu, Huilian Qiao, Maohui Yan et al.
4 citations
Frontiers in Immunology
Neuroinflammation and Neurodegeneration Mechanisms
3.37
article

Exploring the role of LOX family in glioma progression and immune modulation

Hengheng Zhang, Xiaolong Hu, Huilian Qiao, Maohui Yan, Chen Liu, Yingjie Wang, Nan Du, Hongqi Li, Zhiguang Fu
article en
4 citations

Abstract

The LOX family is overexpressed in glioma and is associated with poor prognosis and altered immune infiltration patterns. These findings highlight the LOX family as a promising prognostic marker and therapeutic target, particularly for enhancing the effectiveness of immunotherapy in glioma treatment.

Frontiers in ImmunologyVol. 16
Chinese PLA General Hospital (CN), Beijing Geriatric Hospital (CN), 307th Hospital of Chinese People’s Liberation Army (CN), Chinese People's Liberation Army (CN), Air Force Medical University (CN)
Openalex Percentile: Top 8%
Neuroinflammation and Neurodegeneration Mechanisms
3.37
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Exploring the role of LOX family in glioma progression and immune modulation — Hengheng Zhang, Xiaolong Hu, et al. · Frontiers in Immunology (2025) | TGRS Research Map | TGRS