Investigation of the role of GEM in systemic lupus erythematosus through multi-omics joint analysis
GEM is highly differentially expressed in fibroblast subpopulations within SLE, and its altered expression impacts fibroblast proliferation and migration. GEM may regulate fibroblast activity and apoptosis, potentially contributing to the progression of SLE.
Authors
- Hanxin Zhang (ORCID: https://orcid.org/0000-0001-5069-634X)
- Zongwen Shuai (ORCID: https://orcid.org/0000-0002-5708-6509)
- Yuxuan Shang
- Xiaolei Li (ORCID: https://orcid.org/0000-0002-2697-6496)
- Xiao Zhang (ORCID: https://orcid.org/0000-0001-7842-9489)
- Hanren Dai
- Ruofei Chen (ORCID: https://orcid.org/0000-0002-3330-4129)
Institutions
- Shandong University of Traditional Chinese Medicine (CN)
- Anhui Medical University (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
- Second Affiliated Hospital of Anhui Medical University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-04-09
- DOI
- https://doi.org/10.3389/fimmu.2025.1569605
- Citations
- 1
- Primary Topic
- Systemic Lupus Erythematosus Research
- Type
- article
- Field-Weighted Citation Impact
- 1.67