Inverse association between triglyceride–glucose index and maximal oxygen uptake in US young and middle-aged population: a cross-sectional study

In the US young and middle-aged population, the TyG index was significantly adversely associated with VO<sub>2</sub>max levels. Females may exert an interaction on TyG. Evidence supported DBP, WBC, and CRP as intervening variables through which the TyG index exerts its influence on VO<sub>2</sub>max. HGB may overrule the potential inverse association between the TyG index and VO<sub>2</sub>max.<b>NCHS IRB/ERB Protocol Number</b>: Protocol #98-12.

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Journal
Frontiers in Cardiovascular Medicine
Published
2025-04-09
DOI
https://doi.org/10.3389/fcvm.2025.1583614
Primary Topic
Cardiovascular Function and Risk Factors
Type
article
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article

Inverse association between triglyceride–glucose index and maximal oxygen uptake in US young and middle-aged population: a cross-sectional study

Shangan Cai, Qiang Ren, Yongfeng Li, Dan Li et al.
Frontiers in Cardiovascular Medicine
Cardiovascular Function and Risk Factors
article

Inverse association between triglyceride–glucose index and maximal oxygen uptake in US young and middle-aged population: a cross-sectional study

Shangan Cai, Qiang Ren, Yongfeng Li, Dan Li, Bin Zhang, Li Dong, Junxing Lai, Peng Wang
article en

Abstract

In the US young and middle-aged population, the TyG index was significantly adversely associated with VO<sub>2</sub>max levels. Females may exert an interaction on TyG. Evidence supported DBP, WBC, and CRP as intervening variables through which the TyG index exerts its influence on VO<sub>2</sub>max. HGB may overrule the potential inverse association between the TyG index and VO<sub>2</sub>max.<b>NCHS IRB/ERB Protocol Number</b>: Protocol #98-12.

Frontiers in Cardiovascular MedicineVol. 12
Sun Yat-sen University (CN), The First Affiliated Hospital, Sun Yat-sen University (CN), Jiangmen Central Hospital (CN)
Zero hunger
Openalex Percentile: Top 88%
Cardiovascular Function and Risk Factors
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Inverse association between triglyceride–glucose index and maximal oxygen uptake in US young and middle-aged population: a cross-sectional study — Shangan Cai, Qiang Ren, et al. · Frontiers in Cardiovascular Medicine (2025) | TGRS Research Map | TGRS